Sidee u shaqeeyaa fayraska fayraska?
Sidee u shaqeeyaa fayraska fayraska?
Anonim

Halkii, side loo yaqaan a vector hidde ahaan waxaa loo farsameeyay si loo bixiyo hidda-wadaha. Waa hubaal fayraska waxaa inta badan loo isticmaalaa sida vectors sababtoo ah waxay gudbin karaan hiddo-wadaha cusub iyagoo caabuqa unugyada. Mid kale fayraska, sida adenoviruses, waxay soo bandhigaan DNA-da xudunta unugyada, laakiin DNA-da kuma jiraan koromosoomyada.

Ka sokow, waa maxay vector-ka fayrasku?

Fayraska fayraska waa qalab ay caadiyan isticmaalaan bayoolajiyada molecular si ay u gaarsiiyaan walxaha hidde-sidaha unugyada. Nidaamkan waxaa lagu samayn karaa gudaha noolaha (in vivo) ama dhaqanka unugyada (in vitro). Fayrasyada waxay horumariyeen habab molecular oo khaas ah si ay si hufan ugu qaadaan genom-yadooda gudaha unugyada ay qaadsiiyaan.

Intaa waxaa dheer, sidee buu u shaqeeyaa daaweynta hidda-wadaha fayraska? Daaweynta hidda-socodka waa soo kordhin cusub hiddo-sideyaasha Unugyada bukaanka si ay u beddelaan maqan ama cilladaysan hiddo-sideyaasha. Baarayaasha sida caadiga ah samee tan iyadoo la isticmaalayo a fayruus si ay u qaadaan hidde xamuulka galay unugyada, sababtoo ah taasi waa waxa fayraska u kobcay samee iyaga oo leh hidde maaddo.

Halkan, waa maxay faa'iidooyinka iyo khasaarooyinka isticmaalka fayraska?

Falalka Oncoretroviral
Faa'iidooyinka Khasaaro
Xididdada fayraska
Faa'iidooyinka Khasaaro
Gudbinta hidde-sidaha si hufan oo deggan Heerarka beddelka ee ilaa 90% ee HSC-yada Heerarka sare ee muujinta transgenes-ka titers Sare (>108 TU/ml) Khibrad caafimaad oo ballaadhan oo ay sabab u tahay AIDS U nugul saamaynta booska koromosoomyada

Waa maxay fayraska aan fayraska ahayn?

Maya-Cudurka fayraska. Maya-fayraska waa DNA plasmids oo loo geyn karo unugyada bartilmaameedka ah sida DNA qaawan ama iyada oo lala xiriirinayo xeryahooda kala duwan sida liposomes, gelatin ama polyamine nanospheres. Ka: Dib-u-soo-noolaynta iyo Dayactirka Wadnaha, 2014.

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